Publications

Found 154 results
Type [ Year(Asc)]
2020
K Bulaklak, and CA Gersbach. "The once and future gene therapy." Nature communications 11, no. 1 (2020).
A Dicks, C-L Wu, N Steward, SS Adkar, CA Gersbach, and F Guilak. "Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter." Stem cell research & therapy 11, no. 1 (2020).
M Mao, C-C Chang, A Pickar-Oliver, LD Cervia, L Wang, J Ji, PB Liton, CA Gersbach, and F Yuan. "Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo." Adv Biosyst 4, no. 8 (2020).
BD Cosgrove, and CA Gersbach. "Unwinding the Role of FACT in Cas9-based Genome Editing." Molecular cell 79, no. 3 (2020): 365-367.
2019
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular therapy : the journal of the American Society of Gene Therapy 27, no. 9 (2019): 1568-1585.
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney et al. "An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature communications 10, no. 1 (2019).
L-F Chen, YT Lin, DA Gallegos, MF Hazlett, M Gómez-Schiavon, MG Yang, B Kalmeta, AS Zhou, L Holtzman, CA Gersbach et al. "Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes." Cell Rep 26, no. 5 (2019): 1174-1188.e5.
J Huang, M Chen, ES Xu, L Luo, Y Ma, W Huang, W Floyd, TS Klann, SY Kim, CA Gersbach et al. "Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D." Sci Rep 9, no. 1 (2019).
DD Kocak, EA Josephs, V Bhandarkar, SS Adkar, JB Kwon, and CA Gersbach. "Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature biotechnology 37, no. 6 (2019): 657-666.
JB Kwon, and CA Gersbach. "Jumping at the chance for precise DNA integration." Nature biotechnology 37, no. 9 (2019): 1004-1006.
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, JN Robinson-Hamm, K Bulaklak, RM Castellano Rivera, JH Collier et al. "Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
A Pickar-Oliver, and CA Gersbach. "The next generation of CRISPR-Cas technologies and applications." Nature reviews. Molecular cell biology 20, no. 8 (2019): 490-507.
SS Adkar, C-L Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, and F Guilak. "Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, MJ Sitton, CE Nelson, A Barrera, LC Bartelt et al. "Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells." In Nat Biotechnol, 1493-1501. Vol. 37. 2019.
2018
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, TB Lessa, A Dai, K Zhang, GJ Jenkins et al. "AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." JCI insight 3, no. 23 (2018).
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular therapy : the journal of the American Society of Gene Therapy 26, no. 2 (2018): 334-336.
TS Klann, JB Black, and CA Gersbach. "CRISPR-based methods for high-throughput annotation of regulatory DNA." Current opinion in biotechnology 52 (2018): 32-41.
L Holtzman, and CA Gersbach. Editing the Epigenome: Reshaping the Genomic Landscape.. Vol. 19., 2018.
DD Kocak, and CA Gersbach. "From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
CA Gersbach. "Gene delivery and biomedical engineering." Current Opinion in Biomedical Engineering 7 (2018): iii - v.
AK Pickar, and CA Gersbach. "Gene therapies for hemophilia hit the mark in clinical trials." Nature medicine 24, no. 2 (2018): 121-122.
NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, and F Guilak. "Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue engineering. Part A 24, no. 19-20 (2018): 1531-1544.
IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, SM Leichter, LC Bartelt, WH Majoros, L Song, A Safi et al. "Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Res 28, no. 9 (2018): 1272-1284.
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, CM Vockley, WH Majoros, A Safi, L Song et al. "Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Syst 7, no. 2 (2018): 146-160.e7.
CA Gersbach, and R Barrangou. "Pulling the genome in opposite directions to dissect gene networks." Genome biology 19, no. 1 (2018).

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