Publications
The once and future gene therapy." Nature communications 11, no. 1 (2020).
"Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter." Stem cell research & therapy 11, no. 1 (2020).
"Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo." Adv Biosyst 4, no. 8 (2020).
"Unwinding the Role of FACT in Cas9-based Genome Editing." Molecular cell 79, no. 3 (2020): 365-367.
"AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular therapy : the journal of the American Society of Gene Therapy 27, no. 9 (2019): 1568-1585.
"An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature communications 10, no. 1 (2019).
"Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes." Cell Rep 26, no. 5 (2019): 1174-1188.e5.
"Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D." Sci Rep 9, no. 1 (2019).
"Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature biotechnology 37, no. 6 (2019): 657-666.
"Jumping at the chance for precise DNA integration." Nature biotechnology 37, no. 9 (2019): 1004-1006.
"Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
"The next generation of CRISPR-Cas technologies and applications." Nature reviews. Molecular cell biology 20, no. 8 (2019): 490-507.
"Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
"Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells." In Nat Biotechnol, 1493-1501. Vol. 37. 2019.
"AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." JCI insight 3, no. 23 (2018).
"Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular therapy : the journal of the American Society of Gene Therapy 26, no. 2 (2018): 334-336.
"CRISPR-based methods for high-throughput annotation of regulatory DNA." Current opinion in biotechnology 52 (2018): 32-41.
"Editing the Epigenome: Reshaping the Genomic Landscape.. Vol. 19., 2018.
From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
"Gene delivery and biomedical engineering." Current Opinion in Biomedical Engineering 7 (2018): iii - v.
"Gene therapies for hemophilia hit the mark in clinical trials." Nature medicine 24, no. 2 (2018): 121-122.
"Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue engineering. Part A 24, no. 19-20 (2018): 1531-1544.
"Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Res 28, no. 9 (2018): 1272-1284.
"Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Syst 7, no. 2 (2018): 146-160.e7.
"Pulling the genome in opposite directions to dissect gene networks." Genome biology 19, no. 1 (2018).
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