Publications

Found 139 results
Type [ Year(Asc)]
2021
J Seo, DD Kocak, LC Bartelt, CA Williams, A Barrera, CA Gersbach, and TE Reddy. "AP-1 subunits converge promiscuously at enhancers to potentiate transcription." Genome Res 31, no. 4 (2021): 538-550.
JM Walejko, BA Christopher, SB Crown, G-F Zhang, A Pickar-Oliver, T Yoneshiro, MW Foster, S Page, S van Vliet, O Ilkayeva et al. "Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart." Nature Communications 12, no. 1 (2021).
JC Bodle, and CA Gersbach. "CRISPR Clocks: The Times They Are a-Changin'." The Crispr Journal 4, no. 2 (2021): 160-163.
K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, SA Murray, SQ Tsai, RC Wilson, DG Anderson et al. "The NIH Somatic Cell Genome Editing program." Nature 592, no. 7853 (2021): 195-204.
2020
NVN Carullo, RA Phillips Iii, RC Simon, SAR Soto, JE Hinds, AJ Salisbury, JS Revanna, KD Bunner, L Ianov, FA Sultan et al. "Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems." Nucleic Acids Research 48, no. 17 (2020): 9550-9570.
V Gough, and CA Gersbach. "Immunity to Cas9 as an Obstacle to Persistent Genome Editing." Molecular Therapy 28, no. 6 (2020): 1389-1391.
JB Kwon, AR Ettyreddy, A Vankara, JD Bohning, G Devlin, SD Hauschka, A Asokan, and CA Gersbach. "In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy." Molecular Therapy Methods & Clinical Development 19 (2020): 320-329.
JB Black,, S Dube, A Barrera, TS Klann, GA Rice, SS Adkar, SH Soderling, TE Reddy, and CA Gersbach. "Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens." Cell Reports 33, no. 9 (2020).
JB Kwon, A Vankara, AR Ettyreddy, JD Bohning, and CA Gersbach. "Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators." Stem Cell Reports 14, no. 5 (2020): 755-769.
K Bulaklak, and CA Gersbach. "The once and future gene therapy." Nature Communications 11, no. 1 (2020).
A Dicks, C-L Wu, N Steward, SS Adkar, CA Gersbach, and F Guilak. "Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter." Stem Cell Research & Therapy 11, no. 1 (2020).
M Mao, C-C Chang, A Pickar-Oliver, LD Cervia, L Wang, J Ji, PB Liton, CA Gersbach, and F Yuan. "Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo." Advanced Biosystems 4, no. 8 (2020).
BD Cosgrove, and CA Gersbach. "Unwinding the Role of FACT in Cas9-based Genome Editing." Molecular Cell 79, no. 3 (2020): 365-367.
2019
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular Therapy 27, no. 9 (2019): 1568-1585.
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney et al. "An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature Communications 10, no. 1 (2019).
L-F Chen, YT Lin, DA Gallegos, MF Hazlett, M Gómez-Schiavon, MG Yang, B Kalmeta, AS Zhou, L Holtzman, CA Gersbach et al. "Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes." Cell Reports 26, no. 5 (2019): 1174-1188.e5.
J Huang, M Chen, ES Xu, L Luo, Y Ma, W Huang, W Floyd, TS Klann, SY Kim, CA Gersbach et al. "Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D." Scientific Reports 9, no. 1 (2019).
DD Kocak, EA Josephs, V Bhandarkar, SS Adkar, JB Kwon, and CA Gersbach. "Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature Biotechnology 37, no. 6 (2019): 657-666.
JB Kwon, and CA Gersbach. "Jumping at the chance for precise DNA integration." Nature Biotechnology 37, no. 9 (2019): 1004-1006.
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, JN Robinson-Hamm, K Bulaklak, RM Castellano Rivera, JH Collier et al. "Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
A Pickar-Oliver, and CA Gersbach. "The next generation of CRISPR-Cas technologies and applications." Nature Reviews. Molecular Cell Biology 20, no. 8 (2019): 490-507.
SS Adkar, C-L Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, and F Guilak. "Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem Cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, MJ Sitton, CE Nelson, A Barrera, LC Bartelt et al. "Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells." In Nat Biotechnol, 1493-1501. Vol. 37. 2019.
2018
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, TB Lessa, A Dai, K Zhang, GJ Jenkins et al. "AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." Jci Insight 3, no. 23 (2018).
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular Therapy 26, no. 2 (2018): 334-336.

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