Publications

Found 154 results
[ Type(Asc)] Year
Journal Article
T Gaj, CA Gersbach, and CF Barbas. "ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering." Trends in biotechnology 31, no. 7 (2013): 397-405.
JE Phillips, CA Gersbach, and AJ García. "Virus-based gene therapy strategies for bone regeneration." Biomaterials 28, no. 2 (2007): 211-229.
S Chakraborty, H Ji, J Chen, CA Gersbach, and KW Leong. "Vector modifications to eliminate transposase expression following piggyBac-mediated transgenesis." Scientific reports 4 (2014).
BD Cosgrove, and CA Gersbach. "Unwinding the Role of FACT in Cas9-based Genome Editing." Molecular cell 79, no. 3 (2020): 365-367.
JP Tremblay, X Xiao, A Aartsma-Rus, C Barbas, HM Blau, AJ Bogdanove, K Boycott, S Braun, XO Breakefield, JA Bueren et al. "Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases." Molecular therapy : the journal of the American Society of Gene Therapy 21, no. 2 (2013): 266-268.
MP Gemberling, K Siklenka, E Rodriguez, KR Tonn-Eisinger, A Barrera, F Liu, A Kantor, L Li, V Cigliola, MF Hazlett et al. "Transgenic mice for in vivo epigenome editing with CRISPR-based systems." Nat Methods 18, no. 8 (2021): 965-974.
, AM Swartz, MC Brown, A Barrera, McRoberts C Amador, K Siklenka, L Humayun, MA Ter Weele, JM Isaacs, TE Reddy et al. "Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens." Nat Genet 55, no. 12 (2023): 2211-2223.
KA Glass, JM Link, JM Brunger, FT Moutos, CA Gersbach, and F Guilak. "Tissue-engineered cartilage with inducible and tunable immunomodulatory properties." Biomaterials 35, no. 22 (2014): 5921-5931.
KA Glass, JM Link, JM Brunger, FT Moutos, CA Gersbach, and F Guilak. "Tissue-engineered cartilage with inducible and tunable immunomodulatory properties." Biomaterials 35, no. 22 (2014): 5921-5931.
CA Gersbach, and CF Barbas. "Targeted plasmid integration into the Human Genome by engineered recombinases." Topics in Current Genetics 23 (2013): 267-284.
CA Gersbach, T Gaj, RM Gordley, AC Mercer, and CF Barbas. "Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase." Nucleic acids research 39, no. 17 (2011): 7868-7878.
JB Black, AF Adler, H-G Wang, AM D'Ippolito, HA Hutchinson, TE Reddy, GS Pitt, KW Leong, and CA Gersbach. "Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells." Cell Stem Cell 19, no. 3 (2016): 406-414.
CA Gersbach, T Gaj, and CF Barbas. "Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies." Accounts of chemical research 47, no. 8 (2014): 2309-2318.
JB Black, and CA Gersbach. "Synthetic transcription factors for cell fate reprogramming." Current opinion in genetics & development 52 (2018): 13-21.
RM Gordley, CA Gersbach, and CF Barbas. "Synthesis of programmable integrases." Proceedings of the National Academy of Sciences of the United States of America 106, no. 13 (2009): 5053-5058.
P Perez-Pinera, DG Ousterout, JM Brunger, AM Farin, KA Glass, F Guilak, GE Crawford, AJ Hartemink, and CA Gersbach. "Synergistic and tunable human gene activation by combinations of synthetic transcription factors." Nat Methods 10, no. 3 (2013): 239-242.
N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue engineering. Part A 23, no. 15-16 (2017): 738-749.
T Gaj, AC Mercer, CA Gersbach, RM Gordley, and CF Barbas. "Structure-guided reprogramming of serine recombinase DNA sequence specificity." Proceedings of the National Academy of Sciences of the United States of America 108, no. 2 (2011): 510-515.
T Gaj, AC Mercer, CA Gersbach, RM Gordley, and CF Barbas. "Structure-guided reprogramming of serine recombinase DNA sequence specificity." Proceedings of the National Academy of Sciences of the United States of America 108, no. 2 (2011): 498-503.
EA Josephs, DD Kocak, CJ Fitzgibbon, J McMenemy, CA Gersbach, and PE Marszalek. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic acids research 43, no. 18 (2015): 8924-8941.
SS Adkar, C-L Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, and F Guilak. "Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
AM Kabadi, and CA Gersbach. "Special issue on engineered DNA-binding proteins." ACS synthetic biology 3, no. 10 (2014): 702-703.
J Drevs, U Zirrgiebel, CIM Schmidt-Gersbach, K Mross, M Medinger, L Lee, J Pinheiro, J Wood, AL Thomas, C Unger et al. "Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials." Annals of oncology : official journal of the European Society for Medical Oncology 16, no. 4 (2005): 558-565.
TM Gibson, and CA Gersbach. "Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment." Integrative biology : quantitative biosciences from nano to macro 7, no. 6 (2015): 663-671.
TS Klann, GE Crawford, TE Reddy, and CA Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." Methods Mol Biol 1767 (2018): 447-480.

Pages