Publications

Found 154 results
[ Type(Asc)] Year
Journal Article
DG Ousterout, AM Kabadi, PI Thakore, P Perez-Pinera, MT Brown, WH Majoros, TE Reddy, and CA Gersbach. "Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases." Mol Ther 23, no. 3 (2015): 523-532.
DG Ousterout, AM Kabadi, PI Thakore, P Perez-Pinera, MT Brown, WH Majoros, TE Reddy, and CA Gersbach. "Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases." Molecular Therapy 23, no. 3 (2015): 523-532.
CA Gersbach, T Gaj, and CF Barbas. "Comparing genome editing technologies." Genetic Engineering and Biotechnology News 34, no. 5 (2014): 1, 32-34.
L Wang, E Wang, Prado J Balcazar, Z Wu, K Xiang, Y Wang, Q Huang, M Negrete, K-Y Chen, W Li et al. "Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis." Adv Sci (Weinh) 8, no. 19 (2021).
CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, J Teixeira, X Pan, K Zhang, ED Million et al. "Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models." Nature communications 12, no. 1 (2021).
CE Nelson, and CA Gersbach. "Cas9 loosens its grip on off-target sites." Nature Biotechnology 34, no. 3 (2016): 298-299.
JM Walejko, BA Christopher, SB Crown, G-F Zhang, A Pickar-Oliver, T Yoneshiro, MW Foster, S Page, S van Vliet, O Ilkayeva et al. "Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart." Nat Commun 12, no. 1 (2021).
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular therapy : the journal of the American Society of Gene Therapy 26, no. 2 (2018): 334-336.
CA Gersbach,, JM Le Doux, and AJ García. "Biomaterial-mediated retroviral gene transfer using self-assembled monolayers." Biomaterials 28, no. 34 (2007): 5121-5127.
GP Pathak, JI Spiltoir, C Höglund, LR Polstein, S Heine-Koskinen, CA Gersbach, J Rossi, and CL Tucker. "Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2." Nucleic acids research 45, no. 20 (2017).
J Seo, DD Kocak, LC Bartelt, CA Williams, A Barrera, CA Gersbach, and TE Reddy. "AP-1 subunits converge promiscuously at enhancers to potentiate transcription." Genome Res 31, no. 4 (2021): 538-550.
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney et al. "An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature communications 10, no. 1 (2019).
FT Moutos, KA Glass, SA Compton, AK Ross, CA Gersbach, F Guilak, and BT Estes. "Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing." Proceedings of the National Academy of Sciences of the United States of America 113, no. 31 (2016): E4513-E4522.
P Perez-Pinera, DG Ousterout, and CA Gersbach. "Advances in targeted genome editing." Current opinion in chemical biology 16, no. 3-4 (2012): 268-277.
AJ García, RE Guldberg, BA Byers, CA Gersbach, and JE Phillips. "Addressing cell-sourcing limitations with gene therapy." IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society 22, no. 5 (2003): 65-70.
CA Gersbach, and P Perez-Pinera. "Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine." Expert opinion on therapeutic targets 18, no. 8 (2014): 835-839.
AM Kabadi, MK Mejia-Guerra, JD Graef, SZ Khan, EM Walton, X Wang, CA Gersbach, and R Potter. "AAV-based CRISPR-Cas9 genome editing: Challenges and engineering opportunities." Current Opinion in Biomedical Engineering 29 (2024).
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular therapy : the journal of the American Society of Gene Therapy 27, no. 9 (2019): 1568-1585.
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, TB Lessa, A Dai, K Zhang, GJ Jenkins et al. "AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." JCI insight 3, no. 23 (2018).
Conference Paper
KA Glass, JM Brunger, CA Gersbach, and F Guilak. "Tunable expression of IL-1Ra in genetically modified mesenchymal stem cells for cartilage tissue engineering." In Osteoarthritis and Cartilage, S282-S283. Vol. 21. 2013.
A Pickar-Oliver, JB Black, MM Lewis, KJ Mutchnick, TS Klann, KA Gilcrest, MJ Sitton, CE Nelson, A Barrera, LC Bartelt et al. "Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells." In Nat Biotechnol, 1493-1501. Vol. 37. 2019.
P Perez-Pinera, DG Ousterout, JM Brunger, AM Farin, KA Glass, F Guilak, GE Crawford, AJ Hartemink, and CA Gersbach. "Synergistic and Tunable Gene Activation by Combinations of Synthetic Transcription Factors." In MOLECULAR THERAPY, S93. Vol. 21. 2013.
E Schulz, T Bergmann, M Gebbing, V Schildgen, O Schildgen, C Gersbach, and A Ehrhardt. "Mutation Detection Following Non-Homologous End Joining (NHEJ): A Comparison of Different Semi Quantitative and Quantitative Methods." In MOLECULAR THERAPY, S126-S127. Vol. 22. 2014.
J Black, A Adler, H Hutchinson, H Wang, G Pitt, K Leong, and C Gersbach. "Multiplex Gene Activation by CRISPR/Cas9-Based Transcription Factors for the Direct Conversion of Fibroblasts to a Neuronal Phenotype." In Molecular Therapy, S26. Vol. 23. 2015.
N Farhang, JM Brunger, JD Stover, PI Thakore, BD Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "CRISPRi Immunomodulation for Tissue Engineering/Stem Cell Therapies Targeting Intervertebral Disc Degeneration." In TISSUE ENGINEERING PART A, S170. Vol. 21. 2015.

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