Publications

Found 148 results
Type [ Year(Desc)]
2017
BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, G Seydoux, SE Mohr, J Zuber, and N Perrimon. "Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature Reviews. Genetics 18, no. 1 (2017): 24-40.
JB Black, P Perez-Pinera, and CA Gersbach. "Mammalian Synthetic Biology: Engineering Biological Systems." Annual Review of Biomedical Engineering 19 (2017): 249-277.
N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue Engineering. Part A 23, no. 15-16 (2017): 738-749.
2018
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, TB Lessa, A Dai, K Zhang, GJ Jenkins et al. "AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." Jci Insight 3, no. 23 (2018).
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular Therapy 26, no. 2 (2018): 334-336.
TS Klann, JB Black, and CA Gersbach. "CRISPR-based methods for high-throughput annotation of regulatory DNA." Current Opinion in Biotechnology 52 (2018): 32-41.
L Holtzman, and CA Gersbach. Editing the Epigenome: Reshaping the Genomic Landscape.. Vol. 19., 2018.
DD Kocak, and CA Gersbach. "From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
CA Gersbach. "Gene delivery and biomedical engineering." Current Opinion in Biomedical Engineering 7 (2018): iii - v.
AK Pickar, and CA Gersbach. "Gene therapies for hemophilia hit the mark in clinical trials." Nature Medicine 24, no. 2 (2018): 121-122.
NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, and F Guilak. "Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue Engineering. Part A 24, no. 19-20 (2018): 1531-1544.
IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, SM Leichter, LC Bartelt, WH Majoros, L Song, A Safi et al. "Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Res 28, no. 9 (2018): 1272-1284.
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, CM Vockley, WH Majoros, A Safi, L Song et al. "Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Systems 7, no. 2 (2018): 146-160.e7.
CA Gersbach, and R Barrangou. "Pulling the genome in opposite directions to dissect gene networks." Genome Biology 19, no. 1 (2018).
PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, and CA Gersbach. "RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors." Nature Communications 9, no. 1 (2018).
TS Klann, GE Crawford, TE Reddy, and CA Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." Methods Mol Biol 1767 (2018): 447-480.
JB Black, and CA Gersbach. "Synthetic transcription factors for cell fate reprogramming." Current Opinion in Genetics & Development 52 (2018): 13-21.
2019
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular Therapy 27, no. 9 (2019): 1568-1585.
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney et al. "An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature Communications 10, no. 1 (2019).
L-F Chen, YT Lin, DA Gallegos, MF Hazlett, M Gómez-Schiavon, MG Yang, B Kalmeta, AS Zhou, L Holtzman, CA Gersbach et al. "Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes." Cell Reports 26, no. 5 (2019): 1174-1188.e5.
J Huang, M Chen, ES Xu, L Luo, Y Ma, W Huang, W Floyd, TS Klann, SY Kim, CA Gersbach et al. "Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D." Scientific Reports 9, no. 1 (2019).
DD Kocak, EA Josephs, V Bhandarkar, SS Adkar, JB Kwon, and CA Gersbach. "Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature Biotechnology 37, no. 6 (2019): 657-666.
JB Kwon, and CA Gersbach. "Jumping at the chance for precise DNA integration." Nature Biotechnology 37, no. 9 (2019): 1004-1006.
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, JN Robinson-Hamm, K Bulaklak, RM Castellano Rivera, JH Collier et al. "Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
A Pickar-Oliver, and CA Gersbach. "The next generation of CRISPR-Cas technologies and applications." Nature Reviews. Molecular Cell Biology 20, no. 8 (2019): 490-507.

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