Found 150 results
[ Type(Desc)] Year
Journal Article
JB Kwon, A Vankara, AR Ettyreddy, JD Bohning, and CA Gersbach. "Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators." Stem Cell Reports 14, no. 5 (2020): 755-769.
PY Hwang, L Jing, J Chen, F-L Lim, R Tang, H Choi, KM Cheung, MV Risbud, CA Gersbach, F Guilak et al. "N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions." Scientific Reports 6 (2016).
A Pickar-Oliver, and CA Gersbach. "The next generation of CRISPR-Cas technologies and applications." Nature Reviews. Molecular Cell Biology 20, no. 8 (2019): 490-507.
K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, SA Murray, SQ Tsai, RC Wilson, DG Anderson et al. "The NIH Somatic Cell Genome Editing program." Nature 592, no. 7853 (2021): 195-204.
RB Fletcher, LD Stokes, IB Kelly, KM Henderson, IC Vallecillo-Viejo, JM Colazo, BV Wong, F Yu, R d'Arcy, MN Struthers et al. "Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles." Acs Nano 17, no. 17 (2023): 16412-16431.
K Bulaklak, and CA Gersbach. "The once and future gene therapy." Nature Communications 11, no. 1 (2020).
, AM Swartz, MC Brown, A Barrera, CM Amador, K Siklenka, L Humayun, JM Isaacs, TE Reddy, S Nair et al. "Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function." bioRxiv (2023).
JH Lee, KL Shores, JJ Breithaupt, CS Lee, DM Fodera, JB Kwon, AR Ettyreddy, KM Myers, BJ Evison, AK Suchowerska et al. "PCSK9 activation promotes early atherosclerosis in a vascular microphysiological system." Apl Bioengineering 7, no. 4 (2023).
LR Polstein, and CA Gersbach. "Photoregulated gene expression in human cells with light-inducible engineered transcription factors." ASME 2012 Summer Bioengineering Conference, SBC 2012 (2012): 351-352.
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, CM Vockley, WH Majoros, A Safi, L Song et al. "Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Systems 7, no. 2 (2018): 146-160.e7.
A Dicks, C-L Wu, N Steward, SS Adkar, CA Gersbach, and F Guilak. "Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter." Stem Cell Research & Therapy 11, no. 1 (2020).
CA Gersbach, and R Barrangou. "Pulling the genome in opposite directions to dissect gene networks." Genome Biology 19, no. 1 (2018).
DG Ousterout, P Perez-Pinera, PI Thakore, AM Kabadi, MT Brown, X Qin, O Fédrigo, V Mouly, JP Tremblay, and CA Gersbach. "Reading frame correction by targeted genome editing restores dystrophin expression in cells from duchenne muscular dystrophy patients." Molecular Therapy 21, no. 9 (2013): 1718-1726.
M Mao, C-C Chang, A Pickar-Oliver, LD Cervia, L Wang, J Ji, PB Liton, CA Gersbach, and F Yuan. "Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo." Advanced Biosystems 4, no. 8 (2020).
CL Frank, F Liu, R Wijayatunge, L Song, MT Biegler, MG Yang, CM Vockley, A Safi, CA Gersbach, GE Crawford et al. "Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum." Nat Neurosci 18, no. 5 (2015): 647-656.
P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, LR Polstein, PI Thakore, KA Glass, DG Ousterout, KW Leong et al. "RNA-guided gene activation by CRISPR-Cas9-based transcription factors." Nature Methods 10, no. 10 (2013): 973-976.
PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, and CA Gersbach. "RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors." Nature Communications 9, no. 1 (2018).
JP Beyersdorf, S Bawage, N Iglesias, HE Peck, RA Hobbs, JA Wroe, C Zurla, CA Gersbach, and PJ Santangelo. "Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators." Acs Nano 16, no. 4 (2022): 5660-5671.
TM Gibson, and CA Gersbach. "The role of single-cell analyses in understanding cell lineage commitment." Biotechnology Journal 8, no. 4 (2013): 397-407.
CA Gersbach, BA Byers, GK Pavlath, and AJ García. "Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype." Experimental Cell Research 300, no. 2 (2004): 406-417.
CA Gersbach. "Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype." Exp. Cell Res. 300 (2004): 406-417.
CA Gersbach, BA Byers, GK Pavlath, RE Guldberg, and AJ García. "Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro." Biotechnology and Bioengineering 88, no. 3 (2004): 369-378.
CA Gersbach, JE Phillips, RE Guldberg, and AJ García. "Runx2-genetically engineered cells for bone tissue engineering." Proceedings of the 2005 Summer Bioengineering Conference 2005 (2005): 603-604.
CA Gersbach, BA Byers, RE Guldberg, GK Pavlath, and AJ García. "Runx2-stimulated transdifferentiation of primary skeletal myoblasts into an osteoblastic mineralizing phenotype for bone tissue engineering." Transactions - 7th World Biomaterials Congress (2004).
JM Brunger, NPT Huynh, CM Guenther, P Perez-Pinera, FT Moutos, J Sanchez-Adams, CA Gersbach, and F Guilak. "Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage." Proceedings of the National Academy of Sciences of the United States of America 111, no. 9 (2014): E798-E806.