Publications

Found 97 results
Type [ Year(Desc)]
2016
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues." Arthritis and Rheumatology 69, no. 5 (2016): 1111-1121.
PI Thakore, and CA Gersbach. "Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors." Methods in molecular biology (Clifton, N.J.) 1338 (2016): 71-88.
DG Ousterout, and CA Gersbach. "The Development of TALE Nucleases for Biotechnology." Methods in molecular biology (Clifton, N.J.) 1338 (2016): 27-42.
J Lee, L Xu, TM Gibson, CA Gersbach, and BA Sullenger. "Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts." Biochemical and Biophysical Research Communications 478, no. 3 (2016): 1484-1490.
PI Thakore, JB Black, IB Hilton, and CA Gersbach. "Editing the epigenome: technologies for programmable transcription and epigenetic modulation." Nature Methods 13, no. 2 (2016): 127-137.
CE Nelson, and CA Gersbach. "Engineering Delivery Vehicles for Genome Editing." Annual Review of Chemical and Biomolecular Engineering 7, no. 1 (2016): 637-662.
JN Robinson-Hamm, and CA Gersbach. "Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy." Human Genetics 135, no. 9 (2016): 1029-1040.
IB Hilton, and CA Gersbach. "Genetic engineering: Chemical control for CRISPR editing." Nature Chemical Biology 13, no. 1 (2016): 2-3.
ML Maeder, and CA Gersbach. "Genome-editing Technologies for Gene and Cell Therapy." Molecular Therapy 24, no. 3 (2016): 430-446.
CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RM Castellano Rivera, S Madhavan, X Pan, FA Ran, WX Yan et al. "In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy." Science 351, no. 6271 (2016): 403-407.
DJ Landau, ED Brooks, P Perez-Pinera, H Amarasekara, A Mefferd, S Li, A Bird, CA Gersbach, and DD Koeberl. "In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA." Molecular Therapy 24, no. 4 (2016): 697-706.
BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, G Seydoux, SE Mohr, J Zuber, and N Perrimon. "Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature Reviews Genetics 18, no. 1 (2016): 24-40.
PY Hwang, L Jing, J Chen, FL Lim, R Tang, H Choi, KM Cheung, MV Risbud, CA Gersbach, F Guilak et al. "N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions." Scientific Reports 6 (2016).
EA Josephs, DD Kocak, CJ Fitzgibbon, J McMenemy, CA Gersbach, and PE Marszalek. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic Acids Research 44, no. 5 (2016).
JB Black, AF Adler, HG Wang, AM D'Ippolito, HA Hutchinson, TE Reddy, GS Pitt, KW Leong, and CA Gersbach. "Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells." Cell Stem Cell 19, no. 3 (2016): 406-414.
2017
N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue Engineering, Part A 23, no. 15-16 (2017): 738-749.
TS Klann, JB Black, M Chellappan, A Safi, L Song, IB Hilton, GE Crawford, TE Reddy, and CA Gersbach. "CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome." Nature Biotechnology 35, no. 6 (2017): 561-568.
R Barrangou, and CA Gersbach. "Expanding the CRISPR Toolbox: Targeting RNA with Cas13b." Molecular Cell 65, no. 4 (2017): 582-584.
J Huang, M Chen, MJ Whitley, H-C Kuo, ES Xu, A Walens, YM Mowery, D Van Mater, WC Eward, DM Cardona et al. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature Communications 8 (2017).
SS Adkar, JM Brunger, VP Willard, C-L Wu, CA Gersbach, and F Guilak. "Genome Engineering for Personalized Arthritis Therapeutics." Trends in Molecular Medicine 23, no. 10 (2017): 917-931.
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs." Stem Cell Reports 8, no. 5 (2017): 1202-1213.
JB Black, P Perez-Pinera, and CA Gersbach. "Mammalian Synthetic Biology: Engineering Biological Systems." Annual Review of Biomedical Engineering 19, no. 1 (2017): 249-277.

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