Publications
Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Res 28, no. 9 (2018): 1272-1284.
"Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation." Journal of cell science 119, no. Pt 3 (2006): 581-591.
"Highly active zinc-finger nucleases by extended modular assembly." Genome research 23, no. 3 (2013): 530-538.
"Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements." Nat Methods 12, no. 12 (2015): 1143-1149.
"How vinculin regulates force transmission." Proceedings of the National Academy of Sciences of the United States of America 110, no. 24 (2013): 9788-9793.
"A humanized mouse model for adeno-associated viral gene therapy." Nat Commun 15, no. 1 (2024).
"Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2." Journal of cellular biochemistry 102, no. 6 (2007): 1458-1471.
"Immunity to Cas9 as an Obstacle to Persistent Genome Editing." Molecular therapy : the journal of the American Society of Gene Therapy 28, no. 6 (2020): 1389-1391.
"In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts." Journal of cellular biochemistry 100, no. 5 (2007): 1324-1336.
"In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy." Mol Ther Methods Clin Dev 19 (2020): 320-329.
"In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy." Science 351, no. 6271 (2016): 403-407.
"In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA." Mol Ther 24, no. 4 (2016): 697-706.
"Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies." Nucleic Acids Res 45, no. 20 (2017): 11684-11699.
"Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature biotechnology 37, no. 6 (2019): 657-666.
"Inducible regulation of Runx2-stimulated osteogenesis." Gene therapy 13, no. 11 (2006): 873-882.
"Jumping at the chance for precise DNA integration." Nature biotechnology 37, no. 9 (2019): 1004-1006.
"Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells." Tissue engineering. Part A 21, no. 7-8 (2015): 1261-1274.
"A light-inducible CRISPR-Cas9 system for control of endogenous gene activation." Nature Chemical Biology 11, no. 3 (2015): 198-200.
"Light-inducible gene regulation with engineered zinc finger proteins." Methods in molecular biology (Clifton, N.J.) 1148 (2014): 89-107.
"Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors." Journal of the American Chemical Society 134, no. 40 (2012): 16480-16483.
"Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
"Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature reviews. Genetics 18, no. 1 (2017): 24-40.
"Mammalian Synthetic Biology: Engineering Biological Systems." Annual review of biomedical engineering 19 (2017): 249-277.
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