Publications

Found 106 results
[ Type(Desc)] Year
Journal Article
LR Polstein, and CA Gersbach. "Photoregulated gene expression in human cells with light-inducible engineered transcription factors." ASME 2012 Summer Bioengineering Conference, SBC 2012 (2012): 351-352.
DG Ousterout, P Perez-Pinera, PI Thakore, AM Kabadi, MT Brown, X Qin, O Fédrigo, V Mouly, JP Tremblay, and CA Gersbach. "Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients." Molecular Therapy 21, no. 9 (2013): 1718-1726.
CL Frank, F Liu, R Wijayatunge, L Song, MT Biegler, MG Yang, CM Vockley, A Safi, CA Gersbach, GE Crawford et al. "Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum." Nature Neuroscience 18, no. 5 (2015): 647-656.
P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, LR Polstein, PI Thakore, KA Glass, DG Ousterout, KW Leong et al. "RNA-guided gene activation by CRISPR-Cas9-based transcription factors." Nature Methods 10, no. 10 (2013): 973-976.
TM Gibson, and CA Gersbach. "The role of single-cell analyses in understanding cell lineage commitment." Biotechnology Journal 8, no. 4 (2013): 397-407.
CA Gersbach, BA Byers, GK Pavlath, and AJ García. "Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype." Experimental Cell Research 300, no. 2 (2004): 406-417.
CA Gersbach. "Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype." Exp. Cell Res. 300 (2004): 406-417.
CA Gersbach, BA Byers, GK Pavlath, RE Guldberg, and AJ García. "Runx2/Cbfa1-genetically engineered skeletal myoblasts mineralize collagen scaffolds in vitro." Biotechnology & Bioengineering 88, no. 3 (2004): 369-378.
CA Gersbach, JE Phillips, RE Guldberg, and AJ García. "Runx2-genetically engineered cells for bone tissue engineering." Proceedings of the 2005 Summer Bioengineering Conference 2005 (2005): 603-604.
CA Gersbach, BA Byers, RE Guldberg, GK Pavlath, and AJ García. "Runx2-stimulated transdifferentiation of primary skeletal myoblasts into an osteoblastic mineralizing phenotype for bone tissue engineering." Transactions - 7th World Biomaterials Congress (2004).
JM Brunger, NP Huynh, CM Guenther, P Perez-Pinera, FT Moutos, J Sanchez-Adams, CA Gersbach, and F Guilak. "Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage." Proceedings of the National Academy of Sciences of USA 111, no. 9 (2014): E798-E806.
TS Klann, GE Crawford, TE Reddy, and CA Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." Methods in molecular biology (Clifton, N.J.) 1767 (2018): 447-480.
TM Gibson, and CA Gersbach. "Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment." Integrative Biology 7, no. 6 (2015): 663-671.
J Drevs, U Zirrgiebel, CIM Schmidt-Gersbach, K Mross, M Medinger, L Lee, J Pinheiro, J Wood, AL Thomas, C Unger et al. "Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials." Annals of Oncology 16, no. 4 (2005): 558-565.
AM Kabadi, and CA Gersbach. "Special issue on engineered DNA-binding proteins." ACS Synthetic Biology 3, no. 10 (2014): 702-703.
EA Josephs, DD Kocak, CJ Fitzgibbon, J McMenemy, CA Gersbach, and PE Marszalek. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic Acids Research 44, no. 5 (2016).
EA Josephs, DD Kocak, CJ Fitzgibbon, J McMenemy, CA Gersbach, and PE Marszalek. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic Acids Research 43, no. 18 (2015): 8924-8941.
T Gaj, AC Mercer, CA Gersbach, RM Gordley, and CFB III. "Structure-guided reprogramming of serine recombinase DNA sequence specificity." Proceedings of the National Academy of Sciences of USA 108, no. 2 (2011): 510-515.
T Gaj, AC Mercer, CA Gersbach, RM Gordley, and CF Barbas. "Structure-guided reprogramming of serine recombinase DNA sequence specificity." Proceedings of the National Academy of Sciences of USA 108, no. 2 (2011): 498-503.
P Perez-Pinera, DG Ousterout, JM Brunger, AM Farin, KA Glass, F Guilak, GE Crawford, AJ Hartemink, and CA Gersbach. "Synergistic and tunable human gene activation by combinations of synthetic transcription factors." Nature Methods 10, no. 3 (2013): 239-242.
RM Gordley, CA Gersbach, and CF Barbas. "Synthesis of programmable integrases." Proceedings of the National Academy of Sciences of USA 106, no. 13 (2009): 5053-5058.
CA Gersbach, T Gaj, and CF Barbas. "Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies." Accounts of Chemical Research 47, no. 8 (2014): 2309-2318.
JB Black, AF Adler, HG Wang, AM D'Ippolito, HA Hutchinson, TE Reddy, GS Pitt, KW Leong, and CA Gersbach. "Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells." Cell Stem Cell 19, no. 3 (2016): 406-414.
CA Gersbach, T Gaj, RM Gordley, AC Mercer, and CF Barbas. "Targeted plasmid integration into the human genome by an engineered zinc-finger recombinase." Nucleic Acids Research 39, no. 17 (2011): 7868-7878.
CA Gersbach, and CFB III. "Targeted plasmid integration into the Human Genome by engineered recombinases." Topics in Current Genetics 23 (2013): 267-284.

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