Publications
Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries." Biomaterials 26, no. 22 (2005): 4523-4531.
"Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector." Nucleic acids research 42, no. 19 (2014).
"Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy." Nat Commun 6 (2015): 6244-.
"Multicenter integrated analysis of noncoding CRISPRi screens." Nat Methods (2024).
"Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness." bioRxiv (2024).
"Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens." Cell Rep 33, no. 9 (2020).
"Mammalian Synthetic Biology: Engineering Biological Systems." Annual review of biomedical engineering 19 (2017): 249-277.
"Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature reviews. Genetics 18, no. 1 (2017): 24-40.
"Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
"Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors." Journal of the American Chemical Society 134, no. 40 (2012): 16480-16483.
"Light-inducible gene regulation with engineered zinc finger proteins." Methods in molecular biology (Clifton, N.J.) 1148 (2014): 89-107.
"A light-inducible CRISPR-Cas9 system for control of endogenous gene activation." Nature Chemical Biology 11, no. 3 (2015): 198-200.
"Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells." Tissue engineering. Part A 21, no. 7-8 (2015): 1261-1274.
"Jumping at the chance for precise DNA integration." Nature biotechnology 37, no. 9 (2019): 1004-1006.
"Inducible regulation of Runx2-stimulated osteogenesis." Gene therapy 13, no. 11 (2006): 873-882.
"Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature biotechnology 37, no. 6 (2019): 657-666.
"Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies." Nucleic Acids Res 45, no. 20 (2017): 11684-11699.
"In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA." Mol Ther 24, no. 4 (2016): 697-706.
"In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy." Science 351, no. 6271 (2016): 403-407.
"In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy." Mol Ther Methods Clin Dev 19 (2020): 320-329.
"In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts." Journal of cellular biochemistry 100, no. 5 (2007): 1324-1336.
"Immunity to Cas9 as an Obstacle to Persistent Genome Editing." Molecular therapy : the journal of the American Society of Gene Therapy 28, no. 6 (2020): 1389-1391.
"Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2." Journal of cellular biochemistry 102, no. 6 (2007): 1458-1471.
"A humanized mouse model for adeno-associated viral gene therapy." Nat Commun 15, no. 1 (2024).
"How vinculin regulates force transmission." Proceedings of the National Academy of Sciences of the United States of America 110, no. 24 (2013): 9788-9793.
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