Publications

Found 102 results
[ Type(Desc)] Year
Journal Article
ML Maeder, and CA Gersbach. "Genome-editing Technologies for Gene and Cell Therapy." Molecular Therapy 24, no. 3 (2016): 430-446.
LR Polstein, P Perez-Pinera, DD Kocak, CM Vockley, P Bledsoe, L Song, A Safi, GE Crawford, TE Reddy, and CA Gersbach. "Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators." Genome research 25, no. 8 (2015): 1158-1169.
JE Phillips, CA Gersbach, AM Wojtowicz, and AJ García. "Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation." Journal of cell science 119, no. Pt 3 (2006): 581-591.
MS Bhakta, IM Henry, DG Ousterout, KT Das, SH Lockwood, JF Meckler, MC Wallen, A Zykovich, Y Yu, H Leo et al. "Highly active zinc-finger nucleases by extended modular assembly." Genome research 23, no. 3 (2013): 530-538.
PI Thakore, AM D'Ippolito, L Song, A Safi, NK Shivakumar, AM Kabadi, TE Reddy, GE Crawford, and CA Gersbach. "Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements." Nature Methods 12, no. 12 (2015): 1143-1149.
DW Dumbauld, TT Lee, A Singh, J Scrimgeour, CA Gersbach, EA Zamir, J Fu, CS Chen, JE Curtis, SW Craig et al. "How vinculin regulates force transmission." Proceedings of the National Academy of Sciences of USA 110, no. 24 (2013): 9788-9793.
S Pregizer, A Barski, CA Gersbach, AJ García, and B Frenkel. "Identification of novel Runx2 targets in osteoblasts: cell type-specific BMP-dependent regulation of Tram2." Journal of Cellular Biochemistry 102, no. 6 (2007): 1458-1471.
CA Gersbach, RE Guldberg, and AJ García. "In vitro and in vivo osteoblastic differentiation of BMP-2- and Runx2-engineered skeletal myoblasts." Journal of Cellular Biochemistry 100, no. 5 (2007): 1324-1336.
CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RM Castellano Rivera, S Madhavan, X Pan, FA Ran, WX Yan et al. "In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy." Science 351, no. 6271 (2016): 403-407.
DJ Landau, ED Brooks, P Perez-Pinera, H Amarasekara, A Mefferd, S Li, A Bird, CA Gersbach, and DD Koeberl. "In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA." Molecular Therapy 24, no. 4 (2016): 697-706.
D Manandhar, L Song, A Kabadi, JB Kwon, LE Edsall, M Ehrlich, K Tsumagari, CA Gersbach, GE Crawford, and R Gordân. "Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies." Nucleic Acids Research 45, no. 20 (2017): 11684-11699.
CA Gersbach, JM Le Doux, RE Guldberg, and AJ García. "Inducible regulation of Runx2-stimulated osteogenesis." Gene Therapy 13, no. 11 (2006): 873-882.
BO Diekman, PI Thakore, SK O'Connor, VP Willard, JM Brunger, N Christoforou, KW Leong, CA Gersbach, and F Guilak. "Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells." Tissue Engineering, Part A 21, no. 7-8 (2015): 1261-1274.
LR Polstein, and CA Gersbach. "A light-inducible CRISPR-Cas9 system for control of endogenous gene activation." Nature Chemical Biology 11, no. 3 (2015): 198-200.
LR Polstein, and CA Gersbach. "Light-inducible gene regulation with engineered zinc finger proteins." Methods in molecular biology (Clifton, N.J.) 1148 (2014): 89-107.
LR Polstein, and CA Gersbach. "Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors." Journal of the American Chemical Society 134, no. 40 (2012): 16480-16483.
BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, G Seydoux, SE Mohr, J Zuber, and N Perrimon. "Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature Reviews Genetics 18, no. 1 (2016): 24-40.
JB Black, P Perez-Pinera, and CA Gersbach. "Mammalian Synthetic Biology: Engineering Biological Systems." Annual Review of Biomedical Engineering 19, no. 1 (2017): 249-277.
DG Ousterout, AM Kabadi, PI Thakore, WH Majoros, TE Reddy, and CA Gersbach. "Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy." Nature Communications 6 (2015): 6244-.
AM Kabadi, DG Ousterout, IB Hilton, and CA Gersbach. "Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector." Nucleic Acids Research 42, no. 19 (2014).
MA Lan, CA Gersbach, KE Michael, BG Keselowsky, and AJ García. "Myoblast proliferation and differentiation on fibronectin-coated self assembled monolayers presenting different surface chemistries." Biomaterials 26, no. 22 (2005): 4523-4531.
PY Hwang, L Jing, J Chen, FL Lim, R Tang, H Choi, KM Cheung, MV Risbud, CA Gersbach, F Guilak et al. "N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions." Scientific Reports 6 (2016).
LR Polstein, and CA Gersbach. "Photoregulated gene expression in human cells with light-inducible engineered transcription factors." ASME 2012 Summer Bioengineering Conference, SBC 2012 (2012): 351-352.
DG Ousterout, P Perez-Pinera, PI Thakore, AM Kabadi, MT Brown, X Qin, O Fédrigo, V Mouly, JP Tremblay, and CA Gersbach. "Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients." Molecular Therapy 21, no. 9 (2013): 1718-1726.
CL Frank, F Liu, R Wijayatunge, L Song, MT Biegler, MG Yang, CM Vockley, A Safi, CA Gersbach, GE Crawford et al. "Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum." Nature Neuroscience 18, no. 5 (2015): 647-656.

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