Found 154 results
[ Type(Desc)] Year
Journal Article
NVN Carullo, RA Phillips Iii, RC Simon, SAR Soto, JE Hinds, AJ Salisbury, JS Revanna, KD Bunner, L Ianov, FA Sultan et al. "Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems." Nucleic acids research 48, no. 17 (2020): 9550-9570.
R Yan, V Cigliola, KA Oonk, Z Petrover, S DeLuca, DW Wolfson, A Vekstein, MA Mendiola, G Devlin, M Bishawi et al. "An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair." Cell stem cell 30, no. 1 (2023): 96-111.e6.
IB Hilton, AM D'Ippolito, CM Vockley, PI Thakore, GE Crawford, TE Reddy, and CA Gersbach. "Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers." Nat Biotechnol 33, no. 5 (2015): 510-517.
DG Ousterout, P Perez-Pinera, PI Thakore, AM Kabadi, MT Brown, X Qin, O Fédrigo, V Mouly, JP Tremblay, and CA Gersbach. "Erratum: Reading Frame correction by targeted genome editing restores dystrophin expression in cells from duchenne muscular dystrophy patients (Molecular Therapy (2013) 21 (1718-1726) DOI: 10.1038/mt.2013.111)." Molecular Therapy 21, no. 11 (2013): 2130.
R Barrangou, and CA Gersbach. "Expanding the CRISPR Toolbox: Targeting RNA with Cas13b." Molecular cell 65, no. 4 (2017): 582-584.
DD Kocak, and CA Gersbach. "From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
A Pickar-Oliver, V Gough, JD Bohning, S Liu, JN Robinson-Hamm, H Daniels, WH Majoros, G Devlin, A Asokan, and CA Gersbach. "Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy." Mol Ther 29, no. 11 (2021): 3243-3257.
CA Gersbach. "Gene delivery and biomedical engineering." Current Opinion in Biomedical Engineering 7 (2018): iii - v.
CL Duvall, A Prokop, CA Gersbach, and JM Davidson. "Gene Delivery into Cells and Tissues." (2013): 687-723.
Perez P Pinera, DG Ousterout, MT Brown, and CA Gersbach. "Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases." Nucleic Acids Research 40, no. 8 (2012): 3741-3752.
P Perez-Pinera, DG Ousterout, MT Brown, and CA Gersbach. "Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases." Nucleic Acids Research 40, no. 8 (2012): 3741-3752.
AK Pickar, and CA Gersbach. "Gene therapies for hemophilia hit the mark in clinical trials." Nature medicine 24, no. 2 (2018): 121-122.
JN Robinson-Hamm, and CA Gersbach. "Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy." Human genetics 135, no. 9 (2016): 1029-1040.
J Huang, M Chen, MJ Whitley, H-C Kuo, ES Xu, A Walens, YM Mowery, D Van Mater, WC Eward, DM Cardona et al. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nat Commun 8 (2017).
IB Hilton, and CA Gersbach. "Genetic engineering: Chemical control for CRISPR editing." Nature chemical biology 13, no. 1 (2017): 2-3.
CA Gersbach, JE Phillips, and AJ García. "Genetic engineering for skeletal regenerative medicine." Annual review of biomedical engineering 9 (2007): 87-119.
NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, and F Guilak. "Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue engineering. Part A 24, no. 19-20 (2018): 1531-1544.
JA Doudna, and CA Gersbach. "Genome editing: the end of the beginning." Genome biology 16 (2015).
CE Nelson, JN Robinson-Hamm, and CA Gersbach. "Genome engineering: a new approach to gene therapy for neuromuscular disorders." Nature reviews. Neurology 13, no. 11 (2017): 647-661.
SS Adkar, JM Brunger, VP Willard, C-L Wu, CA Gersbach, and F Guilak. "Genome Engineering for Personalized Arthritis Therapeutics." Trends in molecular medicine 23, no. 10 (2017): 917-931.
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs." Stem cell reports 8, no. 5 (2017): 1202-1213.
CA Gersbach. "Genome engineering: the next genomic revolution." Nature methods 11, no. 10 (2014): 1009-1011.
ML Maeder, and CA Gersbach. "Genome-editing Technologies for Gene and Cell Therapy." Molecular therapy : the journal of the American Society of Gene Therapy 24, no. 3 (2016): 430-446.
J Huang, M Chen, ES Xu, L Luo, Y Ma, W Huang, W Floyd, TS Klann, SY Kim, CA Gersbach et al. "Genome-wide CRISPR Screen to Identify Genes that Suppress Transformation in the Presence of Endogenous KrasG12D." Sci Rep 9, no. 1 (2019).
LR Polstein, P Perez-Pinera, DD Kocak, CM Vockley, P Bledsoe, L Song, A Safi, GE Crawford, TE Reddy, and CA Gersbach. "Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators." Genome Res 25, no. 8 (2015): 1158-1169.