Publications

Found 92 results
Type [ Year(Asc)]
2015
Hilton, IB, D'Ippolito, AM, Vockley, CM, Thakore, PI, Crawford, GE, Reddy, TE, and Gersbach, CA. "Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers." Nature Biotechnology 33, no. 5 (2015): 510-517.
Doudna, JA, and Gersbach, CA. "Genome editing: the end of the beginning." Genome Biology 16, no. 1 (2015).
Polstein, LR, Perez-Pinera, P, Kocak, DD, Vockley, CM, Bledsoe, P, Song, L, Safi, A, Crawford, GE, Reddy, TE, and Gersbach, CA. "Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators." Genome research 25, no. 8 (2015): 1158-1169.
Thakore, PI, D'Ippolito, AM, Song, L, Safi, A, Shivakumar, NK, Kabadi, AM, Reddy, TE, Crawford, GE, and Gersbach, CA. "Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements." Nature Methods 12, no. 12 (2015): 1143-1149.
Diekman, BO, Thakore, PI, O'Connor, SK, Willard, VP, Brunger, JM, Christoforou, N, Leong, KW, Gersbach, CA, and Guilak, F. "Knockdown of the cell cycle inhibitor p21 enhances cartilage formation by induced pluripotent stem cells." Tissue Engineering, Part A 21, no. 7-8 (2015): 1261-1274.
Polstein, LR, and Gersbach, CA. "A light-inducible CRISPR-Cas9 system for control of endogenous gene activation." Nature Chemical Biology 11, no. 3 (2015): 198-200.
Ousterout, DG, Kabadi, AM, Thakore, PI, Majoros, WH, Reddy, TE, and Gersbach, CA. "Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy." Nature Communications 6 (2015): 6244-.
Black, J, Adler, A, Hutchinson, H, Wang, H, Pitt, G, Leong, K, and Gersbach, C. "Multiplex Gene Activation by CRISPR/Cas9-Based Transcription Factors for the Direct Conversion of Fibroblasts to a Neuronal Phenotype." In Molecular Therapy, S26. Vol. 23., 2015.
Frank, CL, Liu, F, Wijayatunge, R, Song, L, Biegler, MT, Yang, MG, Vockley, CM, Safi, A, Gersbach, CA, Crawford, GE et al. "Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum." Nature Neuroscience 18, no. 5 (2015): 647-656.
Gibson, TM, and Gersbach, CA. "Single-molecule analysis of myocyte differentiation reveals bimodal lineage commitment." Integrative Biology 7, no. 6 (2015): 663-671.
Josephs, EA, Kocak, DD, Fitzgibbon, CJ, McMenemy, J, Gersbach, CA, and Marszalek, PE. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic Acids Research 43, no. 18 (2015): 8924-8941.
2014
Gersbach, CA, and Perez-Pinera, P. "Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine." Expert Opinion on Therapeutic Targets 18, no. 8 (2014): 835-839.
Gersbach, CA, Gaj, T, and Barbas, CF. "Comparing Genome Editing Technologies." Genetic Engineering and Biotechnology News 34, no. 5 (2014): 1, 32-34.
High, K, Gregory, PD, and Gersbach, C. "CRISPR technology for gene therapy." Nature Medicine 20, no. 5 (2014): 476-477.
Chakraborty, S, Ji, H, Kabadi, AM, Gersbach, CA, Christoforou, N, and Leong, KW. "A CRISPR/Cas9-based system for reprogramming cell lineage specification." Stem Cell Reports 3, no. 6 (2014): 940-947.
Kabadi, AM, and Gersbach, CA. "Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression." Methods 69, no. 2 (2014): 188-197.
Kabadi, AM, and Gersbach, CA. "Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression." Methods 69, no. 2 (2014): 188-197.
Gersbach, CA. "Genome engineering: the next genomic revolution." Nature Methods 11, no. 10 (2014): 1009-1011.
Polstein, LR, and Gersbach, CA. "Light-inducible gene regulation with engineered zinc finger proteins." Methods in molecular biology (Clifton, N.J.) 1148 (2014): 89-107.
Kabadi, AM, Ousterout, DG, Hilton, IB, and Gersbach, CA. "Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector." Nucleic Acids Research 42, no. 19 (2014).
Schulz, E, Bergmann, T, Gebbing, M, Schildgen, V, Schildgen, O, Gersbach, C, and Ehrhardt, A. "Mutation Detection Following Non-Homologous End Joining (NHEJ): A Comparison of Different Semi Quantitative and Quantitative Methods." In Molecular Therapy, S126-S127. Vol. 22., 2014.
Brunger, JM, Huynh, NP, Guenther, CM, Perez-Pinera, P, Moutos, FT, Sanchez-Adams, J, Gersbach, CA, and Guilak, F. "Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage." Proceedings of the National Academy of Sciences of USA 111, no. 9 (2014): E798-E806.
Kabadi, AM, and Gersbach, CA. "Special issue on engineered DNA-binding proteins." ACS Synthetic Biology 3, no. 10 (2014): 702-703.
Gersbach, CA, Gaj, T, and Barbas, CF. "Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies." Accounts of Chemical Research 47, no. 8 (2014): 2309-2318.
Glass, KA, Link, JM, Brunger, JM, Moutos, FT, Gersbach, CA, and Guilak, F. "Tissue-engineered cartilage with inducible and tunable immunomodulatory properties." Biomaterials 35, no. 22 (2014): 5921-5931.

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