Title | Unwinding the Role of FACT in Cas9-based Genome Editing. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | BD Cosgrove, and CA Gersbach |
Journal | Molecular Cell |
Volume | 79 |
Issue | 3 |
Start Page | 365 |
Pagination | 365 - 367 |
Date Published | 08/2020 |
Abstract | In a recent issue of Molecular Cell, Wang et al. (2020) employ unbiased proteomics approaches and live-cell imaging to reveal a key role for the histone chaperone complex FACT (SPT16 and SSRP1) in governing Cas9 turnover at the DNA target site during genome and epigenome editing. |
DOI | 10.1016/j.molcel.2020.07.016 |
Short Title | Molecular Cell |