Expanding the CRISPR Toolbox: Targeting RNA with Cas13b.

TitleExpanding the CRISPR Toolbox: Targeting RNA with Cas13b.
Publication TypeJournal Article
Year of Publication2017
AuthorsR Barrangou, and CA Gersbach
JournalMolecular Cell
Volume65
Start Page582
Issue4
Pagination582 - 584
Date Published02/2017
Abstract

In this issue of Molecular Cell, Smargon et al. (2017) unearth Cas13b from type VI-B CRISPR-Cas immune systems and characterize its RNA-guided, RNA-targeting activity, including regulation by the novel co-factors Csx27 and Csx28, as well as non-specific collateral RNA damage.

DOI10.1016/j.molcel.2017.02.002
Short TitleMolecular Cell