Found 148 results
Type [ Year(Asc)]
R Yan, V Cigliola, KA Oonk, Z Petrover, S DeLuca, DW Wolfson, A Vekstein, MA Mendiola, G Devlin, M Bishawi et al. "An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair." Cell Stem Cell 30, no. 1 (2023): 96-111.e6.
RB Fletcher, LD Stokes, IB Kelly, KM Henderson, IC Vallecillo-Viejo, JM Colazo, BV Wong, F Yu, R d'Arcy, MN Struthers et al. "Nonviral In Vivo Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles." Acs Nano 17, no. 17 (2023): 16412-16431.
, AM Swartz, MC Brown, A Barrera, McRoberts C Amador, K Siklenka, L Humayun, JM Isaacs, TE Reddy, S Nair et al. "Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function." Biorxiv (2023).
TJ Gonzalez, KE Simon, LO Blondel, MM Fanous, AL Roger, MS Maysonet, GW Devlin, TJ Smith, DK Oh, LP Havlik et al. "Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing." Nature Communications 13, no. 1 (2022).
JP Beyersdorf, S Bawage, N Iglesias, HE Peck, RA Hobbs, JA Wroe, C Zurla, CA Gersbach, and PJ Santangelo. "Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators." Acs Nano 16, no. 4 (2022): 5660-5671.
J Seo, DD Kocak, LC Bartelt, CA Williams, A Barrera, CA Gersbach, and TE Reddy. "AP-1 subunits converge promiscuously at enhancers to potentiate transcription." Genome Res 31, no. 4 (2021): 538-550.
JM Walejko, BA Christopher, SB Crown, G-F Zhang, A Pickar-Oliver, T Yoneshiro, MW Foster, S Page, S van Vliet, O Ilkayeva et al. "Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart." Nature Communications 12, no. 1 (2021).
CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, J Teixeira, X Pan, K Zhang, ED Million et al. "Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models." Nature Communications 12, no. 1 (2021).
L Wang, E Wang, Prado J Balcazar, Z Wu, K Xiang, Y Wang, Q Huang, M Negrete, K-Y Chen, W Li et al. "Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis." Advanced Science (Weinheim, Baden Wurttemberg, Germany) 8, no. 19 (2021).
JC Bodle, and CA Gersbach. "CRISPR Clocks: The Times They Are a-Changin'." The Crispr Journal 4, no. 2 (2021): 160-163.
A Pickar-Oliver, V Gough, JD Bohning, S Liu, JN Robinson-Hamm, H Daniels, WH Majoros, G Devlin, A Asokan, and CA Gersbach. "Full-length dystrophin restoration via targeted exon integration by AAV-CRISPR in a humanized mouse model of Duchenne muscular dystrophy." Molecular Therapy : the Journal of the American Society of Gene Therapy 29, no. 11 (2021): 3243-3257.
AA Abdeen, BD Cosgrove, CA Gersbach, and K Saha. Integrating Biomaterials and Genome Editing Approaches to Advance Biomedical Science.. Vol. 23., 2021.
K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, SA Murray, SQ Tsai, RC Wilson, DG Anderson et al. "The NIH Somatic Cell Genome Editing program." Nature 592, no. 7853 (2021): 195-204.
MP Gemberling, K Siklenka, E Rodriguez, KR Tonn-Eisinger, A Barrera, F Liu, A Kantor, L Li, V Cigliola, MF Hazlett et al. "Transgenic mice for in vivo epigenome editing with CRISPR-based systems." Nat Methods 18, no. 8 (2021): 965-974.
NVN Carullo, RA Phillips Iii, RC Simon, SAR Soto, JE Hinds, AJ Salisbury, JS Revanna, KD Bunner, L Ianov, FA Sultan et al. "Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems." Nucleic Acids Research 48, no. 17 (2020): 9550-9570.
V Gough, and CA Gersbach. "Immunity to Cas9 as an Obstacle to Persistent Genome Editing." Molecular Therapy 28, no. 6 (2020): 1389-1391.
JB Kwon, AR Ettyreddy, A Vankara, JD Bohning, G Devlin, SD Hauschka, A Asokan, and CA Gersbach. "In Vivo Gene Editing of Muscle Stem Cells with Adeno-Associated Viral Vectors in a Mouse Model of Duchenne Muscular Dystrophy." Molecular Therapy Methods & Clinical Development 19 (2020): 320-329.
JB Black,, S Dube, A Barrera, TS Klann, GA Rice, SS Adkar, SH Soderling, TE Reddy, and CA Gersbach. "Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens." Cell Reports 33, no. 9 (2020).
JB Kwon, A Vankara, AR Ettyreddy, JD Bohning, and CA Gersbach. "Myogenic Progenitor Cell Lineage Specification by CRISPR/Cas9-Based Transcriptional Activators." Stem Cell Reports 14, no. 5 (2020): 755-769.
K Bulaklak, and CA Gersbach. "The once and future gene therapy." Nature Communications 11, no. 1 (2020).
A Dicks, C-L Wu, N Steward, SS Adkar, CA Gersbach, and F Guilak. "Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter." Stem Cell Research & Therapy 11, no. 1 (2020).
M Mao, C-C Chang, A Pickar-Oliver, LD Cervia, L Wang, J Ji, PB Liton, CA Gersbach, and F Yuan. "Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo." Advanced Biosystems 4, no. 8 (2020).
BD Cosgrove, and CA Gersbach. "Unwinding the Role of FACT in Cas9-based Genome Editing." Molecular Cell 79, no. 3 (2020): 365-367.
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular Therapy 27, no. 9 (2019): 1568-1585.
BC Evans, RB Fletcher, KV Kilchrist, EA Dailing, AJ Mukalel, JM Colazo, M Oliver, J Cheung-Flynn, CM Brophy, JW Tierney et al. "An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles." Nature Communications 10, no. 1 (2019).