Publications

Found 96 results
Type [ Year(Asc)]
2017
Farhang, N, Brunger, JM, Stover, JD, Thakore, PI, Lawrence, B, Guilak, F, Gersbach, CA, Setton, LA, and Bowles, RD. "CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue Engineering, Part A (2017).
Klann, TS, Black, JB, Chellappan, M, Safi, A, Song, L, Hilton, IB, Crawford, GE, Reddy, TE, and Gersbach, CA. "CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome." Nature Biotechnology 35, no. 6 (2017): 561-568.
Barrangou, R, and Gersbach, CA. "Expanding the CRISPR Toolbox: Targeting RNA with Cas13b." Molecular Cell 65, no. 4 (2017): 582-584.
Huang, J, Chen, M, Whitley, MJ, Kuo, H-C, Xu, ES, Walens, A, Mowery, YM, Van Mater, D, Eward, WC, Cardona, DM et al. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature Communications 8 (2017).
Brunger, JM, Zutshi, A, Willard, VP, Gersbach, CA, and Guilak, F. "Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs." Stem Cell Reports 8, no. 5 (2017): 1202-1213.
Black, JB, Perez-Pinera, P, and Gersbach, CA. "Mammalian Synthetic Biology: Engineering Biological Systems." Annual Review of Biomedical Engineering 19, no. 1 (2017): 249-277.
2016
Moutos, FT, Glass, KA, Compton, SA, Ross, AK, Gersbach, CA, Guilak, F, and Estes, BT. "Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing." Proceedings of the National Academy of Sciences of USA 113, no. 31 (2016): E4513-E4522.
Nelson, CE, and Gersbach, CA. "Cas9 loosens its grip on off-target sites." Nature Biotechnology 34, no. 3 (2016): 298-299.
Brunger, JM, Zutshi, A, Willard, VP, Gersbach, CA, and Guilak, F. "CRISPR/Cas9 editing of induced pluripotent stem cells for engineering inflammation-resistant tissues." Arthritis and Rheumatology 69, no. 5 (2016): 1111-1121.
Thakore, PI, and Gersbach, CA. "Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors." Methods in molecular biology (Clifton, N.J.) 1338 (2016): 71-88.
Ousterout, DG, and Gersbach, CA. "The Development of TALE Nucleases for Biotechnology." Methods in molecular biology (Clifton, N.J.) 1338 (2016): 27-42.
Lee, J, Xu, L, Gibson, TM, Gersbach, CA, and Sullenger, BA. "Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts." Biochemical and Biophysical Research Communications 478, no. 3 (2016): 1484-1490.
Thakore, PI, Black, JB, Hilton, IB, and Gersbach, CA. "Editing the epigenome: technologies for programmable transcription and epigenetic modulation." Nature Methods 13, no. 2 (2016): 127-137.
Nelson, CE, and Gersbach, CA. "Engineering Delivery Vehicles for Genome Editing." Annual Review of Chemical and Biomolecular Engineering 7, no. 1 (2016): 637-662.
Robinson-Hamm, JN, and Gersbach, CA. "Gene therapies that restore dystrophin expression for the treatment of Duchenne muscular dystrophy." Human Genetics 135, no. 9 (2016): 1029-1040.
Hilton, IB, and Gersbach, CA. "Genetic engineering: Chemical control for CRISPR editing." Nature Chemical Biology 13, no. 1 (2016): 2-3.
Maeder, ML, and Gersbach, CA. "Genome-editing Technologies for Gene and Cell Therapy." Molecular Therapy 24, no. 3 (2016): 430-446.
Nelson, CE, Hakim, CH, Ousterout, DG, Thakore, PI, Moreb, EA, Castellano Rivera, RM, Madhavan, S, Pan, X, Ran, FA, Yan, WX et al. "In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy." Science 351, no. 6271 (2016): 403-407.
Landau, DJ, Brooks, ED, Perez-Pinera, P, Amarasekara, H, Mefferd, A, Li, S, Bird, A, Gersbach, CA, and Koeberl, DD. "In Vivo Zinc Finger Nuclease-mediated Targeted Integration of a Glucose-6-phosphatase Transgene Promotes Survival in Mice With Glycogen Storage Disease Type IA." Molecular Therapy 24, no. 4 (2016): 697-706.
Housden, BE, Muhar, M, Gemberling, M, Gersbach, CA, Stainier, DYR, Seydoux, G, Mohr, SE, Zuber, J, and Perrimon, N. "Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature Reviews Genetics 18, no. 1 (2016): 24-40.
Hwang, PY, Jing, L, Chen, J, Lim, FL, Tang, R, Choi, H, Cheung, KM, Risbud, MV, Gersbach, CA, Guilak, F et al. "N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions." Scientific Reports 6 (2016).
Josephs, EA, Kocak, DD, Fitzgibbon, CJ, McMenemy, J, Gersbach, CA, and Marszalek, PE. "Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage." Nucleic Acids Research 44, no. 5 (2016).
Black, JB, Adler, AF, Wang, HG, D'Ippolito, AM, Hutchinson, HA, Reddy, TE, Pitt, GS, Leong, KW, and Gersbach, CA. "Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells." Cell Stem Cell 19, no. 3 (2016): 406-414.
2015
Glass, KA, Ross, AK, Compton, SA, Gersbach, CA, Moutos, FT, Estes, BT, and Guilak, F. "Anatomically-Shaped Tissue-Engineered Cartilage with Tunable and Inducible Anti-Inflammatory Capabilities." In Tissue Engineering, Part A, S330. Vol. 21., 2015.
Ousterout, DG, Kabadi, AM, Thakore, PI, Perez-Pinera, P, Brown, MT, Majoros, WH, Reddy, TE, and Gersbach, CA. "Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases." Molecular Therapy 23, no. 3 (2015): 523-532.

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