Publications

Found 115 results
Type [ Year(Asc)]
2019
SS Adkar, C-L Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, and F Guilak. "Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem Cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
2018
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular Therapy 26, no. 2 (2018): 334-336.
TS Klann, JB Black, and CA Gersbach. "CRISPR-based methods for high-throughput annotation of regulatory DNA." Current Opinion in Biotechnology 52 (2018): 32-41.
L Holtzman, and CA Gersbach. Editing the Epigenome: Reshaping the Genomic Landscape.. Vol. 19., 2018.
DD Kocak, and CA Gersbach. "From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, and F Guilak. "Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue Engineering. Part A 24, no. 19-20 (2018): 1531-1544.
IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, SM Leichter, LC Bartelt, WH Majoros, L Song, A Safi et al. "Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Research 28, no. 9 (2018): 1272-1284.
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, CM Vockley, WH Majoros, A Safi, L Song et al. "Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Systems 7, no. 2 (2018): 146-160.e7.
CA Gersbach, and R Barrangou. "Pulling the genome in opposite directions to dissect gene networks." Genome Biology 19, no. 1 (2018).
PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, and CA Gersbach. "RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors." Nature Communications 9, no. 1 (2018).
TS Klann, GE Crawford, TE Reddy, and CA Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." Methods in Molecular Biology (Clifton, N.J.) 1767 (2018): 447-480.
JB Black, and CA Gersbach. "Synthetic transcription factors for cell fate reprogramming." Current Opinion in Genetics & Development 52 (2018): 13-21.
2017
GP Pathak, JI Spiltoir, C Höglund, LR Polstein, S Heine-Koskinen, CA Gersbach, J Rossi, and CL Tucker. "Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2." Nucleic Acids Research 45, no. 20 (2017).
IB Hilton, and CA Gersbach. "Chemical control for CRISPR editing." Nature Chemical Biology 13, no. 1 (2017): 2-3.
N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue Engineering. Part A 23, no. 15-16 (2017): 738-749.
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues." Arthritis & Rheumatology 69, no. 5 (2017): 1111-1121.
TS Klann, JB Black, M Chellappan, A Safi, L Song, IB Hilton, GE Crawford, TE Reddy, and CA Gersbach. "CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome." Nature Biotechnology 35, no. 6 (2017): 561-568.
LR Polstein, M Juhas, G Hanna, N Bursac, and CA Gersbach. "An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis." Acs Synthetic Biology 6, no. 11 (2017): 2003-2013.
R Barrangou, and CA Gersbach. "Expanding the CRISPR Toolbox: Targeting RNA with Cas13b." Molecular Cell 65, no. 4 (2017): 582-584.
J Huang, M Chen, MJ Whitley, H-C Kuo, ES Xu, A Walens, YM Mowery, D Van Mater, WC Eward, DM Cardona et al. "Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma." Nature Communications 8 (2017).
SS Adkar, JM Brunger, VP Willard, C-L Wu, CA Gersbach, and F Guilak. "Genome Engineering for Personalized Arthritis Therapeutics." Trends in Molecular Medicine 23, no. 10 (2017): 917-931.
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs." Stem Cell Reports 8, no. 5 (2017): 1202-1213.
D Manandhar, L Song, A Kabadi, JB Kwon, LE Edsall, M Ehrlich, K Tsumagari, CA Gersbach, GE Crawford, and R Gordân. "Incomplete MyoD-induced transdifferentiation is associated with chromatin remodeling deficiencies." Nucleic Acids Research 45, no. 20 (2017): 11684-11699.
BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, G Seydoux, SE Mohr, J Zuber, and N Perrimon. "Loss-of-function genetic tools for animal models: cross-species and cross-platform differences." Nature Reviews. Genetics 18, no. 1 (2017): 24-40.
JB Black, P Perez-Pinera, and CA Gersbach. "Mammalian Synthetic Biology: Engineering Biological Systems." Annual Review of Biomedical Engineering 19 (2017): 249-277.

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