Publications

Found 160 results
Type [ Year(Asc)]
2019
ME Nance, R Shi, CH Hakim, NB Wasala, Y Yue, X Pan, T Zhang, CA Robinson, SX Duan, G Yao et al. "AAV9 Edits Muscle Stem Cells in Normal and Dystrophic Adult Mice." Molecular Therapy (2019).
L-F Chen, YT Lin, DA Gallegos, MF Hazlett, M Gómez-Schiavon, MG Yang, B Kalmeta, AS Zhou, L Holtzman, CA Gersbach et al. "Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes." Cell Reports 26, no. 5 (2019): 1174-1188.e5.
DD Kocak, EA Josephs, V Bhandarkar, SS Adkar, JB Kwon, and CA Gersbach. "Increasing the specificity of CRISPR systems with engineered RNA secondary structures." Nature Biotechnology 37, no. 6 (2019): 657-666.
JB Kwon, and CA Gersbach. "Jumping at the chance for precise DNA integration." Nature Biotechnology (2019).
CE Nelson, Y Wu, MP Gemberling, ML Oliver, MA Waller, JD Bohning, JN Robinson-Hamm, K Bulaklak, RM Castellano Rivera, JH Collier et al. "Long-term evaluation of AAV-CRISPR genome editing for Duchenne muscular dystrophy." Nat Med 25, no. 3 (2019): 427-432.
A Pickar-Oliver, and CA Gersbach. "The next generation of CRISPR-Cas technologies and applications." Nature Reviews. Molecular Cell Biology 20, no. 8 (2019): 490-507.
SS Adkar, C-L Wu, VP Willard, A Dicks, A Ettyreddy, N Steward, N Bhutani, CA Gersbach, and F Guilak. "Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing." Stem Cells (Dayton, Ohio) 37, no. 1 (2019): 65-76.
2018
CH Hakim, NB Wasala, CE Nelson, LP Wasala, Y Yue, JA Louderman, TB Lessa, A Dai, K Zhang, GJ Jenkins et al. "AAV CRISPR editing rescues cardiac and muscle function for 18 months in dystrophic mice." Jci Insight 3, no. 23 (2018).
M Gemberling, and CA Gersbach. "Boosting, Not Breaking: CRISPR Activators Treat Disease Models." Molecular Therapy 26, no. 2 (2018): 334-336.
TS Klann, JB Black, and CA Gersbach. "CRISPR-based methods for high-throughput annotation of regulatory DNA." Current Opinion in Biotechnology 52 (2018): 32-41.
L Holtzman, and CA Gersbach. Editing the Epigenome: Reshaping the Genomic Landscape.. Vol. 19., 2018.
DD Kocak, and CA Gersbach. "From CRISPR scissors to virus sensors." Nature 557, no. 7704 (2018): 168-169.
AK Pickar, and CA Gersbach. "Gene therapies for hemophilia hit the mark in clinical trials." Nature Medicine 24, no. 2 (2018): 121-122.
NPT Huynh, JM Brunger, CC Gloss, FT Moutos, CA Gersbach, and F Guilak. "Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds." Tissue Engineering. Part A 24, no. 19-20 (2018): 1531-1544.
IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, SM Leichter, LC Bartelt, WH Majoros, L Song, A Safi et al. "Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding." Genome Res 28, no. 9 (2018): 1272-1284.
AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, CM Vockley, WH Majoros, A Safi, L Song et al. "Pre-established Chromatin Interactions Mediate the Genomic Response to Glucocorticoids." Cell Systems 7, no. 2 (2018): 146-160.e7.
CA Gersbach, and R Barrangou. "Pulling the genome in opposite directions to dissect gene networks." Genome Biology 19, no. 1 (2018).
PI Thakore, JB Kwon, CE Nelson, DC Rouse, MP Gemberling, ML Oliver, and CA Gersbach. "RNA-guided transcriptional silencing in vivo with S. aureus CRISPR-Cas9 repressors." Nature Communications 9, no. 1 (2018).
TS Klann, GE Crawford, TE Reddy, and CA Gersbach. "Screening Regulatory Element Function with CRISPR/Cas9-based Epigenome Editing." Methods Mol Biol 1767 (2018): 447-480.
JB Black, and CA Gersbach. "Synthetic transcription factors for cell fate reprogramming." Current Opinion in Genetics & Development 52 (2018): 13-21.
2017
GP Pathak, JI Spiltoir, C Höglund, LR Polstein, S Heine-Koskinen, CA Gersbach, J Rossi, and CL Tucker. "Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2." Nucleic Acids Research 45, no. 20 (2017).
N Farhang, JM Brunger, JD Stover, PI Thakore, B Lawrence, F Guilak, CA Gersbach, LA Setton, and RD Bowles. "* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments." Tissue Engineering. Part A 23, no. 15-16 (2017): 738-749.
JM Brunger, A Zutshi, VP Willard, CA Gersbach, and F Guilak. "CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues." Arthritis & Rheumatology 69, no. 5 (2017): 1111-1121.
TS Klann, JB Black, M Chellappan, A Safi, L Song, IB Hilton, GE Crawford, TE Reddy, and CA Gersbach. "CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome." Nat Biotechnol 35, no. 6 (2017): 561-568.
LR Polstein, M Juhas, G Hanna, N Bursac, and CA Gersbach. "An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis." Acs Synthetic Biology 6, no. 11 (2017): 2003-2013.

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