News

August 3, 2021 | Duke CAGT

Our work developing new mouse models for CRISPR-based epigenome editing is published in Nature Methods

Matt and Keith's paper on new mice for CRISPR-based epigenome editing is published in Nature Methods! Read more about the work here.

July 10, 2021 | Duke Today

Charlie Awarded Distinguished Professorship

November 18, 2020 | Duke BME News

Charlie is Recognized as 2020 Highly Cited Researcher

September 24, 2020 | GCB News

NIH Grant Creates First Duke Center of Excellence in Genome Sciences

For the first time at Duke, the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, is awarding a Center of Excellence in Genome Science (CEGS) grant, to a group of Duke researchers, providing $14 million of research support over [...]

April 14, 2020 | Duke Research Blog

Gersbach lab research highlighted by Vice President of Research

Dr. Carin reflects on how Duke's fundamental research can turn viruses into marvels.

January 2, 2020 | Pratt News

Duke Researchers Garner Over $6 Million in NIH Funding to Fight Genetic Diseases

Collaborative work using CRISPR genome editing to address the burden of genetic neuromuscular diseases flourishes across Duke.

November 4, 2019 | Duke Engineering News

The Evolution of Genetic Engineering

A Q&A with Charles Gersbach

October 14, 2019 | GCB News

Weapon of Mass Congestion: Protection from Influenz Virus through Gene Control

DARPA recently awarded a grant to a Duke team for a multifaceted research effort aimed at temporarily regulating gene expression using RNA-based techniques that could help protect against pandemic flu by boosting lung resistance to the virus, attacking the virus directly, [...]

The Duke Center for Advanced Genomic Technologies aims to investigate and re-engineer the inner workings of cellular gene regulation machinery and networks

October 1, 2019 | Duke Engineering News

New Duke Center Takes Aim at the Dark Genome

Cascade CRISPR System

September 25, 2019

New CRISPR Class Expands Genetic Engineering Toolbox

The new approach highlights the potential for nearly 90% of natural CRISPR-Cas systems for use in human cells  

CRISPR 50-fold

April 16, 2019 | Duke Engineering News

Engineering "Hairpins" Increases CRISPR Accuracy

Added piece of RNA could improve the precision of CRISPR 50-fold

muscles of similar mice one year after gene-editing treatment (right). Dystrophin production (green) is restored in treated animals, despite therapy-related immune response to the Cas9 editing enzyme (dark spots in white inset).

February 26, 2019 | NIH Director's Blog

More Progress Toward Gene Editing for Kids with Muscular Dystrophy

The Gersbach lab's latest work on gene editing for Duchenne Muscular Dystrophy was highlighted in the NIH Director's Blog.

DNA

February 18, 2019 | Duke Engineering News

Single Genetic Editing Treatment Provides Long-Term Benefits in Mice

Genetic edits and protein restoration in mouse models of Duchenne muscular dystrophy remain viable one year after single CRISPR treatment

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