The Gersbach Lab

Molecular and Cellular Engineering Applied to Regenerative Medicine and Gene Therapy

The Gersbach Lab is focused on engineering new methods for directing cell behavior to regenerate diseased or damaged tissues and treat genetic diseases.  We are particularly interested in developing and applying technologies that manipulate cellular processes at the genetic level.  Our work capitalizes on the products of the Genomic Revolution and modern advances in the fields of genetic reprogramming, gene delivery, protein engineering, stem cell transplantation, and synthetic  biology to create innovative biologic approaches to improving human health.  These studies also facilitate a better understanding of complex processes including organogenesis, cell lineage determination, and gene regulation that will ultimately lead to i mproved design of drugs and biotherapeutics.  Our efforts are catalyzed by i nterdisciplinary collaborations with investigators in engineering and medicine at Duke and other institutions.